Rice University


New Theorem Helps Reveal the Secrets of Tuberculosis

Upon infection with Mycobacterium tuberculosis bacilli (labeled in red), macrophages (nuclei stained blue) accumulate lipid droplets (green). Courtesy of Emma Rey-Jurado/Public Health Research Institute.

A new methodology developed by researchers at Rice and Rutgers universities could help scientists understand how and why a biochemical network doesn't always perform as expected. To test the approach, they analyzed the stress response of bacteria that cause tuberculosis and predicted novel interactions.

The results are described in a PLOS Computational Biology paper published today.

"Over the last several decades, bioscientists have generated a vast amount of information on biochemical networks, a collection of reactions that occur inside living cells," says principal investigator Oleg Igoshin, a Rice associate professor of bioengineering. Read more...

May 26, 2016