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Rice simulations help explain how genomes take form of 3-D chromosomes Rice University scientists trying to solve the ultimate puzzle — the architecture of the human genome — have snapped another piece into place.
Researchers at Rice’s Center for Theoretical Biological Physics have developed a model to explain one part of the mechanism, the folding of chromosomes during a cell’s interphase. Their work offers the possibility of predicting the three-dimensional organization of entire genomes from limited one-dimensional data. Read more...