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International team finds existing drug may halt tumor growth, points way toward more effective treatments.
An international team including Rice University researchers has discovered a way to fight the overexpression of a protein associated with the proliferation of breast cancer. Dialing down the level of the protein NAF-1 and the activity of the iron-sulfur clusters it transports may be key to halting tumor growth, they reported. In a study this week in the Proceedings of the National Academy of Sciences, the researchers suggest a drug that is typically used to treat type 2 diabetes, pioglitazone, has proven effective at controlling NAF-1 levels. Read more...